About the National Notifiable Diseases Surveillance System (NNDSS)

Purpose

NCIRD coordinates for 23 diseases and conditions, including vaccine-preventable diseases (VPDs) and other respiratory diseases and conditions. Data comes through NNDSS, with 20 nationally notifiable and 3 under standardized surveillance.

Surveillance of NCIRD Diseases and Conditions in NNDSS

In cooperation with jurisdiction/state health departments, the National Center for Immunization and Respiratory Diseases (NCIRD) coordinates for 23 diseases and conditions for which data comes through NNDSS, with 20 nationally notifiable and 3 under standardized surveillance, including vaccine-preventable diseases (VPDs) and other respiratory diseases and conditions. CDC is notified by jurisdiction/state health departments of cases of diseases and conditions under national surveillance, as designated by the Council of State and Territorial Epidemiologists (CSTE). NCIRD encourages jurisdiction/state health departments to submit provisional data through NNDSS before completing case investigations; however, cases are included for publication as described in the NNDSS event code list (case status print criteria) approved by CSTE.

CDC publishes NNDSS data weekly in the MMWR and/or CDC WONDER, and yearly in the Annual Summary of Notifiable Diseases. NNDSS data, together with data collected through supplemental surveillance activities, are analyzed by NCIRD staff and are disseminated through surveillance reports, journal manuscripts, CDC WONDER, MMWR Surveillance Summaries, and other publications.

NCIRD Notifiable Conditions

NCIRD subject matter experts coordinate surveillance for the 20 nationally notifiable conditions listed below.

Visit the NNDSS site for a full list of notifiable diseases case definitions.

Notifiable Conditions and Case Definitions

Congenital rubella syndrome (CRS)

COVID-19

Diphtheria

Haemophilus influenzae (invasive disease)

Influenza-associated pediatric mortality

Legionellosis

Measles

Mumps

Neisseria meningitidis (meningococcal disease)

Novel influenza A infections

Pertussis

Poliomyelitis (paralytic)

Poliovirus infections (non-paralytic)

Psittacosis

Rubella

SARS-coronavirus

Streptococcus pneumoniae (invasive pneumococcal disease)

Streptococcal toxic shock syndrome

Tetanus

Varicella

Access CSTE position statements‎

To access CSTE position statements for these conditions, refer to the CSTE Position Statement Archive and enter the position statement number listed on the condition's case definition page (above), title, author, or keyword into the search box.