Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: mmwrq@cdc.gov. Type 508 Accommodation and the title of the report in the subject line of e-mail.
Update: Influenza Vaccine Supply and Recommendations for Prioritization During the 2005--06 Influenza Season
Influenza vaccine distribution delays or vaccine supply shortages have occurred in the United States in three of the last
five influenza seasons (1,2). In response, prioritization has been implemented in previous years to ensure that enough vaccine is available for those at the highest risk for complications from influenza
(3). The information in this report updates
projections of influenza vaccine supply and previous recommendations for priority use of trivalent inactivated influenza vaccine (TIV) during the 2005--06 influenza season
(4).
Four manufacturers now expect to provide influenza vaccine to the U.S. population during the 2005--06 influenza
season (Table). Sanofi Pasteur, Inc., projects production of 60 million doses of TIV. Chiron Corporation projects production of 18--26 million doses of TIV. GlaxoSmithKline (GSK), Inc., whose license application was approved by the Food and
Drug Administration on August 31, 2005, projects production of 8 million doses of TIV. MedImmune Vaccines, Inc., producer
of live attenuated influenza vaccine (LAIV), projects production of approximately 3 million doses. However,
because of the uncertainties regarding production of influenza vaccine, the exact number of available doses and timing of vaccine distribution for the 2005--06 influenza season remain
unknown.
Given the uncertainties in doses and distribution, CDC recommends that the following priority groups receive TIV
until October 24, 2005:
persons aged >65 years with comorbid conditions
residents of long-term--care facilities
persons aged 2--64 years with comorbid conditions
persons aged >65 years without comorbid conditions
children aged 6--23 months
pregnant women
health-care personnel who provide direct patient care
household contacts and out-of-home caregivers of children aged <6 months
These groups correspond to tiers 1A--1C in the table of TIV priority groups that was published previously in the event of vaccination supply disruption (4). Beginning October 24, 2005, all persons will be eligible for vaccination.
The tiered use of prioritization is not recommended for LAIV administration. LAIV may be administered at any time
for vaccination of nonpregnant healthy persons aged 5--49 years, including most health-care personnel, other persons in close contact with groups at high risk for influenza-related complications, and others desiring protection against influenza (5). Additional information is available at
http://www.cdc.gov/flu.
Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of
Health and Human Services.References to non-CDC sites on the Internet are
provided as a service to MMWR readers and do not constitute or imply
endorsement of these organizations or their programs by CDC or the U.S.
Department of Health and Human Services. CDC is not responsible for the content
of pages found at these sites. URL addresses listed in MMWR were current as of
the date of publication.
Disclaimer
All MMWR HTML versions of articles are electronic conversions from ASCII text
into HTML. This conversion may have resulted in character translation or format errors in the HTML version.
Users should not rely on this HTML document, but are referred to the electronic PDF version and/or
the original MMWR paper copy for the official text, figures, and tables.
An original paper copy of this issue can be obtained from the Superintendent of Documents,
U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800.
Contact GPO for current prices.
**Questions or messages regarding errors in formatting should be addressed to
mmwrq@cdc.gov.
