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Test Order
Test Order
Rabies Special Study
CDC-10501
Synonym(s)
None
Test Order Status
This Test Order is currently accepting specimens.
CDC Pre-Approval Needed
Supplemental Information Required
None
Supplemental Form
None
Performed on Specimens from
Human, Animal, and Food/Environmental/Medical Devices/Biologics
Acceptable Sample/ Specimen Type for Testing
Fresh-frozen brain tissues: a full cross section of brain stem and cerebellum (vermis, right and left lateral lobes). If the cerebellum is unavailable, a cross section of right and left hippocampi may be substituted. Serum and (cerebrospinal fluid) CSF. Other specimens may be submitted upon consultation with Rabies Duty Officer.
Minimum Volume Required
Full cross section of brain stem and cerebellum (vermis, right and left lobes). If the cerebellum is unavailable a cross section of right and left hippocampi may be substituted, but brain stem is required. 0.5 to 1.0 mL for serum and CSF. Other volumes may be considered upon consultation with Rabies Duty Officer.
Collection, Storage, and Preservation of Specimen Prior to Shipping
Stored at -80C and should be kept on dry ice.
Transport Medium
To be determined upon consultation with Rabies Duty Officer
Specimen Labeling
This test order can accommodate diagnostic and non-diagnostic specimens. Testing subject to CLIA regulations requires two primary patient identifiers (e.g., patient first and last name, date of birth, unique patient identifier from time of collection, such as medical record number) on the specimen container and on the test requisition.
Research or surveillance specimens may be labeled according to protocol. Labels should not include personally identifiable information. The results reported should NOT be used for diagnosis, treatment, assessment of health or management of the individual patient.
Research or surveillance specimens may be labeled according to protocol. Labels should not include personally identifiable information. The results reported should NOT be used for diagnosis, treatment, assessment of health or management of the individual patient.
Shipping Instructions which Include Specimen Handling Requirements
CDC does not accept routine shipments on weekends or holidays. Please make sure packages arrive Monday - Friday.
Ship to:
<Insert CDC Point of Contact>
Centers for Disease Control and Prevention
RDSB/STATT Unit 89
1600 Clifton Road, NE
Atlanta, GA 30329
<Insert CDC Point of Contact's Telephone Number>
All samples must be shipped in accordance with all applicable local, state and federal regulations.
Methodology
Direct Fluorescent Antibody Test (DFA) for rabies virus antigen, Direct Rapid Immunohistochemistry test (DRIT), Real Time Reverse Transcriptase Polymerase Chain Reaction (RT-PCR), Virus Isolation, Antigenic Typing, Sequence Analysis
Turnaround Time
6 Weeks
Interferences & Limitations
Test is limited by decomposed tissues, due to denaturation of viral proteins and degradation of nucleic acids.
Additional Information
Do not ship specimens without prior consultation and approval. Critical specimens will take less than 3 days to turn around. If testing needs to be repeated results may take up to 12 weeks. Submitters should contact the Rabies Duty Officer by telephone prior to using email and contacting the second CDC POC.
CDC Points of Contact
Version
1.4
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