Figure 4.1 – Outcomes by Birth Cohort Year

At a glance

During 2009–2021, the percentage of infants who received post-exposure prophylaxis (PEP) at birth has remained relatively stable, between 95%–97% each year. The percentage of infants who received post-vaccination serologic testing (PVST) has increased from 59% (6,792 of 11,551 infants managed) in 2009 to 66% (4,621 of 7,041 infants managed) in 2021.
2022 Perinatal Hepatitis B Prevention Program

Outcomes of infants born to persons with hepatitis B and managed by the CDC Perinatal Hepatitis B Prevention Program (PHBPP), by birth cohort year — 56 US Jurisdictions,* 2009–2021

Source: National Perinatal Hepatitis B Prevention Program (PHBPP), Immunization Services Division, CDC.

Infants managed: The number of infants case-managed by CDC Perinatal Hepatitis B Prevention Program

PEP (post-exposure prophylaxis): The number of infants who received PEP at birth (hepatitis B immune globulin and first dose of hepatitis B vaccine) for hepatitis B virus infection.

PVST (post-vaccination serologic testing): The number of infants who received PVST after hepatitis B vaccine series completion.

* Includes 50 states, the District of Columbia, and five cities. Excludes US territories and freely associated states.

Summary

The number of infants whose care was managed in the CDC Perinatal Hepatitis B Prevention Program from 50 states, the District of Columbia, and five cities was 11,551 in 2009 and 7,041 in 2021. During 2009–2021, the percentage of infants who received post-exposure prophylaxis (PEP) at birth has remained relatively stable, between 95%–97% each year. The percentage of infants who received post-vaccination serologic testing (PVST) has increased from 59% (6,792 of 11,551 infants managed) in 2009 to 66% (4,621 of 7,041 infants managed) in 2021.