At a glance
Numbers and rates* of deaths with hepatitis C listed as a cause of death† among residents, by demographic characteristics — United States, 2018–2022
| Characteristics | 2018 No. |
2018 Rate* (95% CI) |
2019 No. |
2019 Rate* (95% CI) |
2020 No. |
2020 Rate* (95% CI) |
2021 No. |
2021 Rate* (95% CI) |
2022 No. |
2022 Rate* (95% CI) |
|---|---|---|---|---|---|---|---|---|---|---|
| Total | 15,713 | 3.72 (3.66–3.78) |
14,242 | 3.33 (3.28–3.39) |
14,863 | 3.45 (3.39–3.50) |
13,895 | 3.18 (3.13–3.24) |
12,717 | 2.89 (2.84–2.94) |
| Age (years) | ||||||||||
| 0–34 | 212 | 0.14 (0.12–0.16) |
170 | 0.11 (0.10–0.13) |
229 | 0.15 (0.13–0.17) |
181 | 0.12 (0.10–0.14) |
172 | 0.12 (0.10–0.13) |
| 35–44 | 499 | 1.21 (1.10–1.31) |
472 | 1.13 (1.03–1.24) |
544 | 1.29 (1.18–1.40) |
587 | 1.35 (1.24–1.46) |
528 | 1.22 (1.11–1.32) |
| 45–54 | 2,040 | 4.9 (4.69–5.11) |
1,676 | 4.1 (3.90–4.30) |
1,555 | 3.85 (3.66–4.04) |
1,443 | 3.55 (3.36–3.73) |
1,112 | 2.73 (2.57–2.89) |
| 55–64 | 7,297 | 17.26 (16.87–17.66) |
6,304 | 14.85 (14.48–15.22) |
6,053 | 14.27 (13.92–14.63) |
5,342 | 12.48 (12.15–12.82) |
4,561 | 10.66 (10.35–10.97) |
| 65–74 | 4,429 | 14.52 (14.10–14.95) |
4,499 | 14.29 (13.87–14.71) |
5,195 | 15.96 (15.53–16.39) |
5,112 | 15.18 (14.77–15.60) |
5,056 | 15.02 (14.60–15.43) |
| ≥75 | 1,235 | 5.63 (5.32–5.94) |
1,117 | 4.95 (4.66–5.24) |
1,286 | 5.56 (5.26–5.87) |
1,230 | 5.55 (5.24–5.85) |
1,287 | 5.8 (5.49–6.12) |
| Sex | ||||||||||
| Male | 11,242 | 5.53 (5.42–5.63) |
10,229 | 4.96 (4.86–5.05) |
10,551 | 5.07 (4.97–5.17) |
9,801 | 4.61 (4.52–4.70) |
8,968 | 4.2 (4.11–4.29) |
| Female | 4,471 | 2.09 (2.02–2.15) |
4,013 | 1.83 (1.77–1.89) |
4,312 | 1.94 (1.88–2.00) |
4,094 | 1.85 (1.79–1.91) |
3,749 | 1.68 (1.62–1.73) |
| Race/ethnicity | ||||||||||
| White, non-Hispanic | 9,798 | 3.36 (3.29–3.43) |
8,996 | 3.08 (3.01–3.15) |
9,333 | 3.18 (3.11–3.25) |
8,752 | 2.98 (2.91–3.04) |
8,107 | 2.72 (2.65–2.78) |
| Black, non-Hispanic | 2,958 | 6.37 (6.14–6.61) |
2,637 | 5.53 (5.32–5.75) |
2,735 | 5.72 (5.50–5.93) |
2,442 | 5.01 (4.81–5.22) |
2,294 | 4.75 (4.55–4.95) |
| Hispanic | 2,190 | 4.64 (4.44–4.84) |
1,865 | 3.84 (3.66–4.02) |
1,979 | 4 (1.28–1.60) |
1,901 | 3.67 (3.50–3.84) |
1,596 | 3.13 (2.98–3.29) |
| Asian/Pacific Islander, non-Hispanic | 278 | 1.4 (1.23–1.56) |
285 | 1.38 (1.21–1.54) |
304 | 1.41 (1.25–1.57) |
293 | 1.32 (1.17–1.48) |
240 | 1.09 (0.95–1.23) |
| Asian, non-Hispanic | 258 | 1.35 (1.18–1.51) |
269 | 1.35 (1.19–1.52) |
295 | 1.41 (1.24–1.57) |
272 | 1.27 (1.12–1.43) |
222 | 1.03 (0.90–1.17) |
| Native Hawaiian or Other Pacific Islander, non-Hispanic | 20 | 3.49 (2.10–5.45) |
16 | UR | S | UR | 21 | 3.23 (2.00–4.94) |
18 | UR |
| American Indian/Alaska Native, non-Hispanic | 240 | 9.21 (8.01–10.41) |
233 | 8.55 (7.42–9.68) |
287 | 10.64 (9.37–11.90) |
279 | 9.99 (8.78–11.19) |
248 | 9.08 (7.92–10.25) |
| Multiple-race, non-Hispanic | 126 | 2.97 (2.44–3.49) |
118 | 2.79 (2.27–3.30) |
113 | 2.54 (2.06–3.01) |
133 | 2.81 (2.33–3.30) |
121 | 2.7 (2.21–3.19) |
| HHS region: Regional office§ | ||||||||||
| Region 1: Boston | 519 | 2.56 (2.33–2.79) |
448 | 2.15 (1.94–2.36) |
467 | 2.34 (2.11–2.56) |
395 | 1.93 (1.73–2.12) |
386 | 1.86 (1.67–2.05) |
| Region 2: New York | 924 | 2.48 (2.31–2.64) |
780 | 2.06 (1.91–2.21) |
819 | 2.11 (1.96–2.26) |
722 | 1.83 (1.69–1.96) |
700 | 1.75 (1.61–1.88) |
| Region 3: Philadelphia | 1,253 | 3.04 (2.87–3.22) |
1,185 | 2.85 (2.68–3.02) |
1,242 | 2.98 (2.81–3.15) |
1,233 | 2.92 (2.75–3.09) |
1,193 | 2.81 (2.65–2.98) |
| Region 4: Atlanta | 3,160 | 3.60 (3.47–3.72) |
2,996 | 3.36 (3.24–3.49) |
3,097 | 3.45 (3.33–3.58) |
2,865 | 3.17 (3.05–3.29) |
2,654 | 2.89 (2.78–3.00) |
| Region 5: Chicago | 1,762 | 2.52 (2.40–2.64) |
1,611 | 2.27 (2.15–2.38) |
1,750 | 2.45 (2.33–2.57) |
1,618 | 2.26 (2.15–2.38) |
1,464 | 2.03 (1.92–2.14) |
| Region 6: Dallas | 2,907 | 5.85 (5.64–6.07) |
2,562 | 5.06 (4.86–5.25) |
2,570 | 4.98 (4.78–5.17) |
2,524 | 4.86 (4.67–5.06) |
2,274 | 4.38 (4.20–4.57) |
| Region 7: Kansas City | 544 | 3.04 (2.78–3.30) |
496 | 2.67 (2.43–2.92) |
500 | 2.66 (2.42–2.90) |
457 | 2.34 (2.12–2.56) |
385 | 2.04 (1.83–2.25) |
| Region 8: Denver | 636 | 4.45 (4.09–4.80) |
600 | 4.1 (3.77–4.44) |
682 | 4.57 (4.22–4.92) |
614 | 4.04 (3.71–4.36) |
569 | 3.75 (3.43–4.06) |
| Region 9: San Francisco | 2,928 | 4.63 (4.46–4.80) |
2,564 | 4.00 (3.84–4.15) |
2,708 | 4.15 (3.99–4.31) |
2,410 | 3.74 (3.59–3.90) |
2,141 | 3.28 (3.14–3.42) |
| Region 10: Seattle | 1,080 | 5.79 (5.43–6.14) |
1,000 | 5.27 (4.94–5.61) |
1,028 | 5.27 (4.94–5.60) |
1,057 | 5.36 (5.03–5.70) |
951 | 4.82 (4.50–5.13) |
Source: CDC, National Center for Health Statistics (NCHS), Provisional Multiple Cause of Death on CDC WONDER Online Database. Rates for 2018–2020 may differ from previously published rates due to the change from bridged-race to single-race categories. Data are reported for non-Hispanic Asian/Pacific Islander persons, and also separately for non-Hispanic Asian persons and non-Hispanic Native Hawaiian persons (shown in italics). Data are based on information from all death certificates filed in the vital records offices of the 50 states and the District of Columbia through the Vital Statistics Cooperative Program. Deaths of nonresidents (for example, nonresident aliens, nationals living abroad, residents of Puerto Rico, Guam, the Virgin Islands, and other US territories) and fetal deaths are excluded. Accessed at CDC Wonder on November 12, 2023. CDC WONDER data set documentation and technical methods can be accessed here and here.
* Rates for race/ethnicity, sex, US Department of Health and Human Services region, and the overall total are age-adjusted per 100,000 US standard population during 2000 by using the following age group distribution (in years): <1, 1–4, 5–14, 15–24, 25–34, 35–44, 45–54, 55–64, 65–74, 75–84, and ≥85. Missing data are not included. For age-adjusted death rates, the age-specific death rate is rounded to one decimal place before proceeding to the next step in the calculation of age-adjusted death rates for NCHS Multiple Cause of Death on CDC WONDER. This rounding step might affect the precision of rates calculated for small numbers of deaths.
† Cause of death is defined as one of the multiple causes of death and is based on the International Classification of Diseases, 10th Revision (ICD-10) codes B17.1 and B18.2 (hepatitis C).
§ US Department of Health and Human Services regions were categorized according to the grouping of states and US territories assigned under each of the 10 Health and Human Services regional offices. For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.
UR: Unreliable rate. Rates where death counts were less than 20 were not displayed because of the instability associated with those rates.
S: Suppressed. In order to prevent revealing information that may identify specific individuals, small data values are not available when the count falls below a ratio of the representative demographic population.
CI: Confidence interval.
Summary
This table summarizes the characteristics of hepatitis C-related deaths among residents in the United States. During 2022, a total of 12,717 hepatitis C-related deaths were reported among US residents in the Provisional US Multiple Cause of Death data from the National Center for Health Statistics, resulting in an age-adjusted mortality rate of 2.89 deaths per 100,000 population.
Hepatitis C-related death rates were highest among persons aged 55–74 years, compared with other age categories, and deaths in this age group accounted for 76% of all hepatitis C-related deaths reported during 2022. Non-Hispanic White persons accounted for 64% of all hepatitis C-listed deaths with a rate of 2.72 deaths per 100,000 population; however, the death rate among non-Hispanic American Indian/Alaska Native persons (9.08 deaths per 100,000 population) and non-Hispanic Black persons (4.75 deaths per 100,000 population) was 3.3 times and 1.7 times the rate among non-Hispanic White persons, respectively. Variations of disease rates by race or ethnicity may reflect systemic cultural, behavioral, environmental, and social factors, including structural racism. The highest hepatitis C-related death rate was reported in US Department of Health and Human Services Region 10 (Alaska, Idaho, Oregon, and Washington), compared with other regions.