Table 3.6 – Chronic – Case Rates by Demographics

At a glance

This table summarizes the counts and rates per 100,000 population of reported cases of chronic hepatitis C overall and by age group, sex, race/ethnicity, urbanicity and US Department of Health and Human Services region.
2022 Hepatitis C Surveillance

Number and rate* of newly reported cases of chronic hepatitis C, by demographic characteristics — United States, 2022

The number and rate of newly reported cases of chronic hepatitis C, by demographic characteristics. The first column lists the demographic characteristics (age, sex, race and ethnicity, urbanicity, and US Department of Health and Human Services region). The second column provides the number of newly reported chronic hepatitis C cases, and the third column provides rates, expressed as reported cases per 100,000 population, for each demographic category during 2022.
Characteristics No. Rate*
Total§ 93,805 40.2
Age (years)
0–19 885 1.6
20–29 10,833 35.0
30–39 25,192 80.2
40–49 18,414 64.9
50–59 15,805 53.5
≥60 22,338 38.9
Sex
Male 60,646 52.5
Female 32,553 27.6
Race/ethnicity
American Indian/Alaska Native, non-Hispanic 1,834 104.8
Asian/Pacific Islander, non-Hispanic 740 6.5
Black, non-Hispanic 9,938 30.6
White, non-Hispanic 47,269 31.3
Hispanic 4,112 13.1
Other 4,704 n/a
Urbanicity 
Urban 71,904 37.1
Rural 21,016 58.5
HHS region**
Region 1: Boston 4,009 26.5
Region 2: New York 6,643 23.0
Region 3: Philadelphia 13,850 44.3
Region 4: Atlanta 27,664 51.7
Region 5: Chicago 12,585 27.4
Region 6: Dallas 12,308 89.4
Region 7: Kansas City 5,713 40.0
Region 8: Denver 4,317 34.2
Region 9: San Francisco 1,846 58.1
Region 10: Seattle 4,870 33.1

Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population.† Reported confirmed cases. For the case definition, see Chronic Hepatitis C.

§ Numbers reported in each category may not add up to the total number of reported cases in a year due to cases with missing data.

¶ Urbanicity was categorized according to the 2013 National Center for Health Statistics (NCHS) urban-rural classification scheme for counties and county-equivalent entities. Large central metro, large fringe metro, medium metro, and small metro counties were grouped as urban. Micropolitan and noncore counties were grouped as rural.

** US Department of Health and Human Services regions were categorized according to the grouping of states and US territories assigned under each of the 10 Health and Human Services regional offices. For the purposes of this report, regions with US territories (Region 2 and Region 9) contain data from states only.

n/a: Not applicable. Rate cannot be calculated due to lack of corresponding denominator.

Summary

During 2022, the rates of newly reported chronic hepatitis C were highest among persons aged 30–39 years, males, non-Hispanic American Indian/Alaska Native persons, those living in rural areas, and persons in US Department of Health and Human Services Region 6 (Arkansas, Louisiana, New Mexico, Oklahoma, and Texas).

Among all newly reported chronic hepatitis C cases during 2022, 27% occurred among persons aged 30–39 years, 65% occurred among males, and 76% occurred in urban areas. Race and ethnicity information was only available for 68,597 (73%) cases of newly reported chronic hepatitis C; after excluding cases with missing race and ethnicity information, 69% of cases occurred among non-Hispanic White persons.

Variations of disease rates by race or ethnicity may reflect systemic cultural, behavioral, environmental, and social factors, including structural racism.