Table 3.1 – Acute – Number & Rates of Cases

At a glance

The national rate of reported acute hepatitis C was 1.5 cases per 100,000 population during 2022, a decrease of over 6% from the rate during 2021.
2022 Hepatitis C Surveillance

Numbers and rates* of reported cases of acute hepatitis C, by state or jurisdiction — United States, 2018–2022

Numbers and rates* of reported cases† of hepatitis A, by state or jurisdiction — United States, 2018–2022

Source: CDC, National Notifiable Diseases Surveillance System.

* Rates per 100,000 population. Beginning in 2021, single-race population estimates are used for rate calculations. For prior years, bridged-race population estimates are used

.† Reported confirmed cases. For the case definition, see Acute Hepatitis C.

—: No reported cases. The reporting jurisdiction did not submit any cases to CDC.

N: Not reportable. The disease or condition was not reportable by law, statue, or regulation in the reporting jurisdiction.

U: Unavailable. The data were unavailable.

Summary

The capacity of each jurisdiction for notifying CDC of acute hepatitis C cases varies considerably on the basis of laws, resources, and infrastructure for conducting viral hepatitis surveillance. During 2022, acute hepatitis C was not a reportable condition in one state (Alaska), cases were unavailable from one state (Arizona), and no cases were reported by two states (Hawaii and North Dakota).

The national rate of reported acute hepatitis C was 1.5 cases per 100,000 population during 2022, a decrease of over 6% from the rate during 2021. During 2022, Maine had the highest rate of reported cases of acute hepatitis C (6.8 cases per 100,000 population). Florida reported the largest number of cases (n = 1,463) — 30% of all reported acute hepatitis C cases during 2022.