Global Health Overview: Fact Sheet

For Everyone

At a glance

CDC helps protect communities, advance health security, and foster a safer, more resilient world for all. In a connected world, early action abroad is critical protection at home.

Person dressed in personal protective equipment in front of a group of birds.

CDC's Global Health Work

America’s first line of defense against health threats that originate overseas

Person dressed in personal protective equipment in front of a group of birds.
CDC's global disease surveillance capabilities allow CDC to continuously track, monitor, and rapidly identify outbreaks that pose a health security threat to the U.S.

Global health security is national security. With overseas offices in more than 60 countries and strong partnerships built over decades, CDC is the first call when health threats emerge. Every outbreak stopped abroad is one less threat to U.S. communities, travelers, and the economy.

By combining scientific expertise, real-time data, laboratory networks, and trained responders, CDC works with countries to detect health threats, guide response decisions, and stop disease spread quickly, ensuring the U.S. is protected from global outbreaks.

Ina connected world, early action abroad is critical protection at home.

This is what global health security looks like:

  • Stopping the spread of deadly diseases at the source before they reach the U.S.
  • Developing effective prevention strategies and medical countermeasures, advancing our understanding of rapidly evolving diseases and science, and protecting Americans at home.
  • Detecting and containing disruptive global outbreaks, limiting their economic impact on the U.S. and saving taxpayer dollars.

Global health security is a “best buy” for America

CDC’s global health efforts deliver a strong return on investment—protecting Americans, strengthening national security, and supporting economic well-being. CDC’s investments in Ebola outbreak responses in sub-Saharan Africa from 2016 - 2023 resulted in:

  • $1 investment in global health security saved at least $4 in U.S. exports
  • $10 billion U.S. export losses avoided
  • 10 Ebola outbreaks contained
  • 120,000 U.S. jobs protected

Prevention

What we do

Addressing health threats abroad allows CDC to understand disease transmission and refine medical countermeasures for domestic preparedness. For example, CDC's efforts globally prevent polio from entering the U.S.

Why this matters

Every dollar spent on prevention saves costs associated with U.S. emergency response, healthcare, and productivity losses—improving the health and livelihoods of communities.

Our Impact

50K+
paralytic polio cases and $2 billion in health costs are averted annually in the U.S. through global polio eradication efforts.

Surveillance

What we do

CDC's global disease surveillance capabilities are early warning systems that allow CDC to continuously track, monitor, and rapidly identify outbreaks that pose a health security threat to the U.S.

Why this matters

Access to global data and early-warning systems provides more time to strengthen U.S. domestic preparedness when a global outbreak occurs.

Our Impact

30+
global health threats monitored daily through event based-surveillance.

Laboratory

What we do

CDC strengthens the speed and ability of labs to identify deadly pathogens that threaten the U.S. The quicker a disease is confirmed, the faster an effective response can be stood up to prevent further spread.

Why this matters

CDC collaborates with global partners to reduce diseases that can be imported into the U.S. from other countries, like neglected tropical diseases, polio, and HIV-drug resistant strains.

Our Impact

1,400
laboratories and testing sites strengthened across 40+ countries.

Response

What we do

CDC's headquarters and overseas offices can pivot staff, public health programs, and platforms to respond immediately when outbreaks begin. CDC experts use deep expertise to stop health threats.

Why this matters

Due in great part to CDC efforts, most people never hear of some outbreaks as they are contained before they spread to the U.S.

Our Impact

61+
active global responses in over 31 countries as of 2026.

Workforce

What we do

CDC trains the world’s leading disease detectives to manage global health threats from any pathogen. These disease detectives investigate outbreaks in real time, identify threats, and prevent them from reaching the U.S.

Why this matters

CDC-trained global public health professionals detect diseases and enhance global preparedness, alleviating the burden on U.S. resources.

Our Impact

25K+
disease detectives trained by CDC in more than 90 countries.

Additional information

Content Source
Global Health Center
About This Page
Published: February 26, 2026
Updated: August 20, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: March 3, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.