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Intravenous Fluids and The Dengue Patient—A Closer Look
Colloid Solutions
Because these large molecules do not easily cross the capillary wall, colloids remain in the intravascular space longer than crystalloids, so less volume is needed for the same effect, reducing the risk for fluid overload. Colloids preserve a high colloid osmotic pressure in the blood, while this parameter is decreased by crystalloids due to hemodilution.
There is controversy concerning actual differences in efficacy. Colloids are also more expensive than crystalloids and are associated with a slightly greater risk of adverse reactions, including allergic reactions.
Nevertheless, colloids are a good option when administration of crystalloids has not reversed the patient’s shock.
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