Module 2.5 – Confirming SARS-CoV-2 reinfection with whole genome sequencing

What to know

This module investigates a case study from California that demonstrates how whole genome sequencing can be used as an investigative tool to identify cases of true reinfection.

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Overview

Presenter: Megan Crumpler, PhD | Laboratory Director Orange County, CA Public Health Laboratory Long Beach City, CA Public Health Laboratory
Download Presentation Slides [PDF - 13 slides]

Additional Resources

  1. Genomic evidence for reinfection with SARS-CoV-2: a case study. Tillett, Lancet Infect Dis, 2021.
  2. Severe acute respiratory syndrome coronavirus 2 reinfection cases corroborated by sequencing. Massachi, et al. Am J Trop Med Hyg, 2021.
  3. Assessment of the risk of SARS-CoV-2 reinfection in an intense re-exposure setting. Abu-Raddad, et al. Clin Infect Dis, 2021.
  4. SARS-CoV-2 sequence characteristics of COVID-19 persistence and reinfection. Choudhary, et al. Clin Infect Dis, 2021.
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Content Source:
National Center for Emerging and Zoonotic Infectious Diseases (NCEZID)