What to know
- ACIP's next meeting will be held on December 4-5, 2025.
- Get meeting information and read draft vote language below.
Summary of anticipated votes
Several votes are planned during the December 4-5, 2025 ACIP meeting.
The vote language shown below is considered draft. All vote language is subject to change and will continue to be updated in advance of the ACIP meeting.
Anticipated votes
ACIP Childhood/Adolescent Immunization Schedule Workgroup
Hepatitis B Vaccination in Children Born to Mothers who test HBsAg-negative
Vote Language, 12/3/25
VOTE 1
ACIP recommends a birth dose of Hepatitis B virus (HBV) vaccine and Hepatitis B Immunoglobulin for infants born to women who test HBsAg-positive. ACIP recommends individual-based decision-making, in consultation with a health care provider, for parents deciding whether to give the HBV vaccine birth dose to infants born to women who are HBsAg-negative. Parents should consult with health care providers and decide when or if their child will begin the HBV vaccine series.A Parents and health care providers should consider vaccine benefits, vaccine risks, and infection risks. For those not receiving the HBV birth dose, it is suggested that the initial dose is administered no earlier than 2 months of age. Y/N
VOTE 2
ACIP reaffirms the current standard of care that a birth dose of HBV vaccine and Hepatitis B Immunoglobulin is administered for infants born to women whose HBsAg status is unknown.
VOTE 3
When evaluating the need for subsequent HBV vaccine dose in children, parents should consult with health care providers to determine if a post-vaccination anti-HBs serology testing should be offered prior to subsequent HBV vaccine dose administration. Serology results should determine whether the established protective anti-HBs titer threshold of ≥10 mIU/mL has been achieved. The cost of this testing should be covered by insurance. Y/N
- Parents and health care providers should also consider whether there are risks, for example, such as a household member is HBsAg-positive or when there is frequent contact with persons who have emigrated from areas where Hepatitis B is common.