ACIP Recommendations: Orthopoxviruses (Smallpox and Mpox) Vaccines

Published in Morbidity and Mortality Weekly Report (MMWR)

The Advisory Committee on Immunization Practices (ACIP) provides advice and guidance to the Director of the CDC regarding use of vaccines and related agents for control of vaccine-preventable diseases in the civilian population of the United States. Recommendations made by the ACIP are reviewed by the CDC Director and, if adopted, are published as official CDC/HHS recommendations in the Morbidity and Mortality Weekly Report (MMWR).

CURRENT Smallpox and Mpox vaccine recommendations

• MMWR, June 3, 2022, / Vol 71(22);734–742
  Use of JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) for Preexposure Vaccination of Persons at Risk for Occupational Exposure to Orthopoxviruses: Recommendations of the Advisory Committee on Immunization Practices — United States, 2022
  Print version
• MMWR, March 17, 2016, Vol 65(10);257–262
  Use of Vaccinia Virus Smallpox Vaccine in Laboratory and Health Care Personnel at Risk for Occupational Exposure to Orthopoxviruses — Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2015
  Print version
• MMWR, February 29, 2008, Vol 57(08);207-208
  Notice to Readers: Newly Licensed Smallpox Vaccine to Replace Old Smallpox Vaccine
  Print version
• MMWR, February 3, 2006, Vol 55(RR-01);1-16
  Surveillance Guidelines for Smallpox Vaccine (vaccinia) Adverse Reactions
  Print version
• MMWR, April 4, 2003, Vol 52(RR-07);1-16
  Recommendations for Using Smallpox Vaccine in a Pre-Event Vaccination Program
  Print version
• MMWR, June 22, 2001, Vol 50(RR10);1-25
  Vaccinia (Smallpox) Vaccine
  Print version

ARCHIVED historical Smallpox and Mpox immunization publications

For your convenience, these archived publications can be used for historical and research purposes.

• MMWR, April 4, 2003, Vol 52(13);282-284
  Notice to Readers: Supplemental Recommendations on Adverse Events Following Smallpox Vaccine in the Pre-Event Vaccination Program: Recommendations of the ACIP
  Print version
• MMWR, March 21, 2003, Vol 52(12);256
  Notice to Readers: National Smallpox Vaccine in Pregnancy Registry
  Print version
• MMWR, February 21, 2003, Vol 52(RR-04);1-28
  Smallpox Vaccination and Adverse Reactions: Guidance for Clinicians
  Print version

Related pages

Petersen BW, Damon IK, Pertowski CA, Meaney-Delman D, Guarnizo JT, Beigi RH, et al. Clinical Guidance for Smallpox Vaccine Use in a Postevent Vaccination Program MMWR. 2015;64(RR02);1-26.