Vaccines and Preventable Diseases:
Typhoid Fever Vaccination
Pronounced (TYE-foid)
If you are traveling to a country where typhoid (Salmonella serotype Typhi) is common, you should consider
being vaccinated against typhoid. Visit a doctor or travel clinic to discuss
your vaccination options.
Remember that you will need to complete your vaccination at least 1 week before you travel so that the vaccine has time to take effect. Typhoid vaccines lose effectiveness after several years; if you were vaccinated in the past, check with your doctor to see if it is time for a booster vaccination.

What You Should Know:
For Health Professionals:
What You Should Know
- Questions and Answers
- Pictures of Typhoid
Warning: Some of these photos are quite graphic. - Just for kids
None specific to typhoid but many related sites of interest to kids. - Fact Sheet

- Travelers information
If you are traveling to a country where typhoid is common...
Vaccination is not usually needed in the U.S. It is usually recommended only for international travelers going to developing countries where exposure to contaminated food or water is likely. If needed, there are currently two vaccines available in the United States. Please consult your doctor or travel clinic to determine which vaccine is right for you.
As with all vaccines, there can be minor reactions, including pain and redness at the injection site, headache, fatigue or a vague feeling of discomfort.
For Health Professionals
Clinical Information on Typhoid
- Technical information
Clinical Features, Etiologic Agent, Incidence, Complications, Transmission, Risk Groups, Surveillance, Trends, Challenges, etc. - NIPINFO answers your questions about Typhoid
- Vaccine administration
- Package inserts
(Vivotif
, Typhim Vi
, and more package inserts...
) NEW Feb 2010 - Precautions and contraindications
Vaccine Recommendations
References and Resources
- Related MMWR articles, links, and references
- CDC - Estimating the Incidence of Typhoid Fever and Other Febrile Illnesses in Developing Countries
- WHO's Typhoid Outbreaks

- Travelers Health: Yellow Book
- Infection control guidelines
- Typhoid Fever Vaccine Safety Surveillance
Clinical Infectious Diseases 2004:38/6 (15 March 2004) p771-923.
http://www.journals.uchicago.edu/CID/journal/ - Typhoid Fever Prevention in Travelers
Clinical Infectious Diseases 2004:39/2 (15 July 2004) p186-191.
http://www.journals.uchicago.edu/CID/journal/
Provider Education
- Podcasts
Immunization-related podcasts; none specifically on typhoid fever
Materials for Patients
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Content last reviewed on May 13, 2009
Content Source: National Center for Immunization and Respiratory Diseases
