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Reported Tuberculosis in the United States, 2021
Table 39. Tuberculosis Risk Factors: Reporting Areas, 2021
| Reporting area | Total cases1 | Contact2 | Non-HIV immunosuppression3,4 | Diabetes mellitus | Post-organ transplantation | TNF-α inhibitors5 | Other6 | None | Unknown or missing | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | ||
| United States7 | 7,882 | 475 | (6.0) | 684 | (8.7) | 1,882 | (23.9) | 52 | (0.7) | 84 | (1.1) | 1,959 | (24.9) | 2,865 | (36.3) | 996 | (12.6) |
| Alabama | 92 | 12 | (13.0) | 3 | (3.3) | 13 | (14.1) | 0 | (0.0) | 0 | (0.0) | 10 | (10.9) | 57 | (62.0) | 0 | (0.0) |
| Alaska | 58 | 20 | (34.5) | 1 | (1.7) | 5 | (8.6) | 0 | (0.0) | 0 | (0.0) | 16 | (27.6) | 24 | (41.4) | 0 | (0.0) |
| Arizona | 129 | 0 | (0.0) | 8 | (6.2) | 31 | (24.0) | 0 | (0.0) | 3 | (2.3) | 42 | (32.6) | 0 | (0.0) | 68 | (52.7) |
| Arkansas | 69 | 28 | (40.6) | 7 | (10.1) | 19 | (27.5) | 0 | (0.0) | 0 | (0.0) | 20 | (29.0) | 15 | (21.7) | 0 | (0.0) |
| California | 1,752 | 69 | (3.9) | 177 | (10.1) | 516 | (29.5) | 16 | (0.9) | 17 | (1.0) | 480 | (27.4) | 691 | (39.4) | 43 | (2.5) |
| Colorado | 58 | 4 | (6.9) | 1 | (1.7) | 3 | (5.2) | 0 | (0.0) | 1 | (1.7) | 16 | (27.6) | 37 | (63.8) | 0 | (0.0) |
| Connecticut | 54 | 2 | (3.7) | 4 | (7.4) | 9 | (16.7) | 0 | (0.0) | 1 | (1.9) | 7 | (13.0) | 37 | (68.5) | 0 | (0.0) |
| Delaware | 41 | 0 | (0.0) | 3 | (7.3) | 12 | (29.3) | 0 | (0.0) | 1 | (2.4) | 26 | (63.4) | 0 | (0.0) | 10 | (24.4) |
| District of Columbia | 18 | 0 | (0.0) | 2 | (11.1) | 3 | (16.7) | 0 | (0.0) | 0 | (0.0) | 5 | (27.8) | 0 | (0.0) | 12 | (66.7) |
| Florida | 500 | 0 | (0.0) | 67 | (13.4) | 105 | (21.0) | 6 | (1.2) | 9 | (1.8) | 0 | (0.0) | 0 | (0.0) | 337 | (67.4) |
| Georgia | 223 | 38 | (17.0) | 13 | (5.8) | 36 | (16.1) | 0 | (0.0) | 3 | (1.3) | 68 | (30.5) | 97 | (43.5) | 3 | (1.3) |
| Hawaii | 106 | 0 | (0.0) | 18 | (17.0) | 52 | (49.1) | 1 | (0.9) | 3 | (2.8) | 10 | (9.4) | 0 | (0.0) | 43 | (40.6) |
| Idaho | 5 | 0 | (0.0) | 1 | (20.0) | 1 | (20.0) | 0 | (0.0) | 0 | (0.0) | 1 | (20.0) | 3 | (60.0) | 0 | (0.0) |
| Illinois | 254 | 23 | (9.1) | 28 | (11.0) | 65 | (25.6) | 1 | (0.4) | 2 | (0.8) | 56 | (22.0) | 107 | (42.1) | 2 | (0.8) |
| Indiana | 127 | 10 | (7.9) | 12 | (9.4) | 34 | (26.8) | 0 | (0.0) | 3 | (2.4) | 80 | (63.0) | 24 | (18.9) | 0 | (0.0) |
| Iowa | 49 | 0 | (0.0) | 3 | (6.1) | 10 | (20.4) | 0 | (0.0) | 0 | (0.0) | 2 | (4.1) | 0 | (0.0) | 37 | (75.5) |
| Kansas | 43 | 0 | (0.0) | 3 | (7.0) | 8 | (18.6) | 1 | (2.3) | 0 | (0.0) | 5 | (11.6) | 0 | (0.0) | 30 | (69.8) |
| Kentucky | 57 | 12 | (21.1) | 7 | (12.3) | 4 | (7.0) | 1 | (1.8) | 0 | (0.0) | 28 | (49.1) | 18 | (31.6) | 0 | (0.0) |
| Louisiana | 86 | 8 | (9.3) | 8 | (9.3) | 21 | (24.4) | 2 | (2.3) | 1 | (1.2) | 18 | (20.9) | 43 | (50.0) | 0 | (0.0) |
| Maine | 14 | 4 | (28.6) | 1 | (7.1) | 2 | (14.3) | 0 | (0.0) | 2 | (14.3) | 3 | (21.4) | 5 | (35.7) | 0 | (0.0) |
| Maryland | 195 | 13 | (6.7) | 14 | (7.2) | 22 | (11.3) | 2 | (1.0) | 1 | (0.5) | 26 | (13.3) | 123 | (63.1) | 9 | (4.6) |
| Massachusetts | 151 | 8 | (5.3) | 18 | (11.9) | 24 | (15.9) | 3 | (2.0) | 2 | (1.3) | 57 | (37.7) | 87 | (57.6) | 6 | (4.0) |
| Michigan | 137 | 0 | (0.0) | 20 | (14.6) | 34 | (24.8) | 2 | (1.5) | 3 | (2.2) | 40 | (29.2) | 0 | (0.0) | 69 | (50.4) |
| Minnesota | 134 | 11 | (8.2) | 17 | (12.7) | 29 | (21.6) | 1 | (0.7) | 2 | (1.5) | 95 | (70.9) | 22 | (16.4) | 0 | (0.0) |
| Mississippi | 46 | 0 | (0.0) | 3 | (6.5) | 9 | (19.6) | 0 | (0.0) | 2 | (4.3) | 7 | (15.2) | 0 | (0.0) | 30 | (65.2) |
| Missouri | 78 | 0 | (0.0) | 11 | (14.1) | 16 | (20.5) | 0 | (0.0) | 1 | (1.3) | 57 | (73.1) | 0 | (0.0) | 17 | (21.8) |
| Montana | 3 | 1 | (33.3) | 1 | (33.3) | 1 | (33.3) | 0 | (0.0) | 0 | (0.0) | 1 | (33.3) | 1 | (33.3) | 0 | (0.0) |
| Nebraska | 22 | 1 | (4.5) | 0 | (0.0) | 5 | (22.7) | 0 | (0.0) | 0 | (0.0) | 4 | (18.2) | 10 | (45.5) | 3 | (13.6) |
| Nevada | 61 | 1 | (1.6) | 5 | (8.2) | 23 | (37.7) | 1 | (1.6) | 0 | (0.0) | 13 | (21.3) | 26 | (42.6) | 0 | (0.0) |
| New Hampshire | 12 | 0 | (0.0) | 1 | (8.3) | 2 | (16.7) | 0 | (0.0) | 1 | (8.3) | 1 | (8.3) | 0 | (0.0) | 9 | (75.0) |
| New Jersey | 292 | 0 | (0.0) | 27 | (9.2) | 65 | (22.3) | 2 | (0.7) | 3 | (1.0) | 63 | (21.6) | 0 | (0.0) | 162 | (55.5) |
| New Mexico | 24 | 3 | (12.5) | 4 | (16.7) | 8 | (33.3) | 0 | (0.0) | 1 | (4.2) | 5 | (20.8) | 7 | (29.2) | 0 | (0.0) |
| New York State8 | 154 | 16 | (10.4) | 15 | (9.7) | 33 | (21.4) | 2 | (1.3) | 0 | (0.0) | 65 | (42.2) | 49 | (31.8) | 12 | (7.8) |
| New York City | 529 | 11 | (2.1) | 45 | (8.5) | 132 | (25.0) | 4 | (0.8) | 1 | (0.2) | 72 | (13.6) | 276 | (52.2) | 27 | (5.1) |
| North Carolina | 178 | 18 | (10.1) | 15 | (8.4) | 32 | (18.0) | 1 | (0.6) | 1 | (0.6) | 108 | (60.7) | 60 | (33.7) | 0 | (0.0) |
| North Dakota | 15 | 2 | (13.3) | 1 | (6.7) | 3 | (20.0) | 0 | (0.0) | 0 | (0.0) | 5 | (33.3) | 7 | (46.7) | 0 | (0.0) |
| Ohio | 150 | 7 | (4.7) | 7 | (4.7) | 19 | (12.7) | 1 | (0.7) | 1 | (0.7) | 26 | (17.3) | 93 | (62.0) | 0 | (0.0) |
| Oklahoma | 69 | 22 | (31.9) | 6 | (8.7) | 17 | (24.6) | 1 | (1.4) | 0 | (0.0) | 12 | (17.4) | 26 | (37.7) | 0 | (0.0) |
| Oregon | 76 | 0 | (0.0) | 6 | (7.9) | 16 | (21.1) | 0 | (0.0) | 1 | (1.3) | 0 | (0.0) | 0 | (0.0) | 54 | (71.1) |
| Pennsylvania | 166 | 4 | (2.4) | 6 | (3.6) | 25 | (15.1) | 1 | (0.6) | 2 | (1.2) | 31 | (18.7) | 103 | (62.0) | 0 | (0.0) |
| Rhode Island | 17 | 3 | (17.6) | 1 | (5.9) | 2 | (11.8) | 0 | (0.0) | 0 | (0.0) | 5 | (29.4) | 7 | (41.2) | 0 | (0.0) |
| South Carolina | 87 | 10 | (11.5) | 11 | (12.6) | 14 | (16.1) | 0 | (0.0) | 5 | (5.7) | 18 | (20.7) | 40 | (46.0) | 1 | (1.1) |
| South Dakota | 12 | 0 | (0.0) | 2 | (16.7) | 3 | (25.0) | 0 | (0.0) | 0 | (0.0) | 6 | (50.0) | 4 | (33.3) | 0 | (0.0) |
| Tennessee | 84 | 10 | (11.9) | 6 | (7.1) | 14 | (16.7) | 0 | (0.0) | 0 | (0.0) | 21 | (25.0) | 42 | (50.0) | 0 | (0.0) |
| Texas | 1,000 | 86 | (8.6) | 46 | (4.6) | 271 | (27.1) | 3 | (0.3) | 6 | (0.6) | 227 | (22.7) | 493 | (49.3) | 11 | (1.1) |
| Utah | 17 | 1 | (5.9) | 0 | (0.0) | 2 | (11.8) | 0 | (0.0) | 2 | (11.8) | 5 | (29.4) | 9 | (52.9) | 0 | (0.0) |
| Vermont | 3 | 0 | (0.0) | 2 | (66.7) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 1 | (33.3) | 0 | (0.0) | 0 | (0.0) |
| Virginia | 161 | 6 | (3.7) | 11 | (6.8) | 46 | (28.6) | 0 | (0.0) | 0 | (0.0) | 37 | (23.0) | 75 | (46.6) | 0 | (0.0) |
| Washington | 199 | 8 | (4.0) | 13 | (6.5) | 54 | (27.1) | 0 | (0.0) | 3 | (1.5) | 36 | (18.1) | 105 | (52.8) | 1 | (0.5) |
| West Virginia | 6 | 1 | (16.7) | 0 | (0.0) | 1 | (16.7) | 0 | (0.0) | 0 | (0.0) | 1 | (16.7) | 3 | (50.0) | 0 | (0.0) |
| Wisconsin | 66 | 2 | (3.0) | 3 | (4.5) | 11 | (16.7) | 0 | (0.0) | 0 | (0.0) | 19 | (28.8) | 38 | (57.6) | 0 | (0.0) |
| Wyoming | 3 | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 2 | (66.7) | 1 | (33.3) | 0 | (0.0) |
| American Samoa | 4 | 0 | (0.0) | 0 | (0.0) | 1 | (25.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 3 | (75.0) |
| Federated States of Micronesia | 71 | 0 | (0.0) | 0 | (0.0) | 8 | (11.3) | 0 | (0.0) | 0 | (0.0) | 6 | (8.5) | 3 | (4.2) | 54 | (76.1) |
| Guam | 58 | 8 | (13.8) | 2 | (3.4) | 26 | (44.8) | 0 | (0.0) | 0 | (0.0) | 10 | (17.2) | 18 | (31.0) | 0 | (0.0) |
| Republic of the Marshall Islands | 118 | 0 | (0.0) | 0 | (0.0) | 41 | (34.7) | 0 | (0.0) | 0 | (0.0) | 4 | (3.4) | 0 | (0.0) | 75 | (63.6) |
| Northern Mariana Islands | 35 | 0 | (0.0) | 0 | (0.0) | 10 | (28.6) | 0 | (0.0) | 0 | (0.0) | 1 | (2.9) | 1 | (2.9) | 23 | (65.7) |
| Puerto Rico | 18 | 0 | (0.0) | 0 | (0.0) | 6 | (33.3) | 0 | (0.0) | 0 | (0.0) | 2 | (11.1) | 0 | (0.0) | 11 | (61.1) |
| Republic of Palau | 6 | 0 | (0.0) | 0 | (0.0) | 2 | (33.3) | 0 | (0.0) | 0 | (0.0) | 1 | (16.7) | 0 | (0.0) | 3 | (50.0) |
| U.S. Virgin Islands | 2 | 0 | (0.0) | 1 | (50.0) | 0 | (0.0) | 0 | (0.0) | 0 | (0.0) | 1 | (50.0) | 0 | (0.0) | 0 | (0.0) |
1One person might have more than one risk factor, therefore the total number of risk factors is greater than the number of cases.
2Includes risk factor responses of “Contact with MDR-TB patient,” “Contact of infectious TB patient,” and “Missed contact.”
3HIV, human immunodeficiency virus.
4Includes risk factor responses of “End-stage renal disease” and “Immunosuppression (not HIV/AIDS)”.
5TNF, tumor necrosis factor
6Includes risk factor responses of “Incomplete LTBI therapy” and “Other.”
7American Samoa, Federated States of Micronesia, Guam, Republic of the Marshall Islands, Northern Mariana Islands, Puerto Rico, Republic of Palau, and U.S. Virgin Islands are not included in the U.S. totals and percentages.
8Excludes New York City.