Reported Tuberculosis in the United States, 2017
Table 24. Characteristics of Tuberculosis Cases in GENType Clusters1, by Alert Levels Based on Log-Likelihood Ratios (LLR)2: United States, 2015–2017
Case Characteristics | Unique | Clustered | Alert Levels for Clustered Cases3 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Non-alerted (LLR <5) | Medium (LLR 5 – <10) | High (LLR ≥10) | |||||||||
No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | ||
Total | 16,770 | 79.7 | 4,259 | 20.3 | 2,473 | 58.1 | 1,036 | 24.3 | 750 | 17.6 | |
Origin of Birth | |||||||||||
U.S-born | 4,169 | 65.7 | 2,179 | 34.3 | 869 | 39.9 | 664 | 30.5 | 646 | 29.6 | |
Non-U.S.–born | 12,585 | 85.9 | 2,072 | 14.1 | 1,598 | 77.1 | 371 | 17.9 | 103 | 5.0 | |
Unknown or Missing | 16 | 66.7 | 8 | 33.3 | 6 | 75.0 | 1 | 12.5 | 1 | 12.5 | |
Race and Ethnicity | |||||||||||
Hispanic or Latino | 4,524 | 77.4 | 1,323 | 22.6 | 823 | 62.2 | 355 | 26.8 | 145 | 11.0 | |
American Indian/Alaska Native | 133 | 46.5 | 153 | 53.5 | 17 | 11.1 | 51 | 33.3 | 85 | 55.6 | |
Asian | 6,608 | 86.8 | 1006 | 13.2 | 868 | 86.3 | 108 | 10.7 | 30 | 3.0 | |
Black or African American | 3,075 | 72.2 | 1,185 | 27.8 | 500 | 42.2 | 325 | 27.4 | 360 | 30.4 | |
Native Hawaiian/Other Pacific Islander | 123 | 63.4 | 71 | 36.6 | 43 | 60.6 | 10 | 14.1 | 18 | 25.4 | |
White | 2,144 | 81.6 | 483 | 18.4 | 207 | 42.9 | 172 | 35.6 | 104 | 21.5 | |
Multiple Race | 116 | 80.6 | 28 | 19.4 | 9 | 32.1 | 11 | 39.3 | 8 | 28.6 | |
Unknown or Missing | 47 | 82.5 | 10 | 17.5 | 6 | 60.0 | 4 | 40.0 | 0 | 0.0 | |
Age Group (Years) | |||||||||||
0–4 | 85 | 43.1 | 112 | 56.9 | 49 | 43.8 | 42 | 37.5 | 21 | 18.8 | |
5–14 | 116 | 61.1 | 74 | 38.9 | 42 | 56.8 | 16 | 21.6 | 16 | 21.6 | |
15–24 | 1,554 | 76.1 | 488 | 23.9 | 282 | 57.8 | 129 | 26.4 | 77 | 15.8 | |
25–44 | 5,056 | 78.8 | 1,361 | 21.2 | 746 | 54.8 | 370 | 27.2 | 245 | 18.0 | |
45–64 | 5,060 | 76.8 | 1,525 | 23.2 | 859 | 56.3 | 348 | 22.8 | 318 | 20.9 | |
≥65 | 4,894 | 87.5 | 699 | 12.5 | 495 | 70.8 | 131 | 18.7 | 73 | 10.4 | |
Unknown | |||||||||||
Disease Site | |||||||||||
Pulmonary Only | 11,889 | 77.8 | 3,399 | 22.2 | 1,923 | 56.6 | 843 | 24.8 | 633 | 18.6 | |
Extrapulmonary | 2,911 | 87.5 | 415 | 12.5 | 279 | 67.2 | 92 | 22.2 | 44 | 10.6 | |
Both | 1,961 | 81.6 | 442 | 18.4 | 269 | 60.9 | 101 | 22.9 | 72 | 16.3 | |
Unknown | 9 | 75.0 | 3 | 25.0 | 2 | 66.7 | 0 | 0.0 | 1 | 33.3 | |
Sputum Smear | |||||||||||
Positive | 7,555 | 76.6 | 2,312 | 23.4 | 1,285 | 55.6 | 621 | 26.9 | 406 | 17.6 | |
Negative | 6,815 | 82.2 | 1,478 | 17.8 | 914 | 61.8 | 292 | 19.8 | 272 | 18.4 | |
Not Done | 2,378 | 83.6 | 467 | 16.4 | 273 | 58.5 | 122 | 26.1 | 72 | 15.4 | |
Unknown or Missing | 22 | 91.7 | 2 | 8.3 | 1 | 50.0 | 1 | 50.0 | 0 | 0.0 | |
Cavitary Disease4 | |||||||||||
Yes | 154 | 76.2 | 48 | 23.8 | 25 | 52.1 | 14 | 29.2 | 9 | 18.8 | |
No | 1,386 | 81.0 | 326 | 19.0 | 200 | 61.3 | 73 | 22.4 | 53 | 16.3 | |
Unknown or Missing | |||||||||||
Homeless Within Past Year | |||||||||||
Yes | 628 | 56.8 | 478 | 43.2 | 195 | 40.8 | 119 | 24.9 | 164 | 34.3 | |
No | 16,051 | 81.0 | 3,757 | 19.0 | 2,264 | 60.3 | 909 | 24.2 | 584 | 15.5 | |
Unknown or Missing | 91 | 79.1 | 24 | 20.9 | 14 | 58.3 | 8 | 33.3 | 2 | 8.3 | |
Excess Alcohol Use Within the Past Year | |||||||||||
Yes | 1,385 | 62.7 | 823 | 37.3 | 329 | 40.0 | 254 | 30.9 | 240 | 29.2 | |
No | 15,157 | 81.8 | 3,370 | 18.2 | 2,102 | 62.4 | 762 | 22.6 | 506 | 15.0 | |
Unknown or Missing | 228 | 77.6 | 66 | 22.4 | 42 | 63.6 | 20 | 30.3 | 4 | 6.1 | |
Injecting Illicit Drug Use Within Past Year | |||||||||||
Yes | 170 | 59.9 | 114 | 40.1 | 42 | 36.8 | 42 | 36.8 | 30 | 26.3 | |
No | 16,410 | 80.1 | 4,067 | 19.9 | 2,380 | 58.5 | 973 | 23.9 | 714 | 17.6 | |
Unknown or Missing | 190 | 70.9 | 78 | 29.1 | 51 | 65.4 | 21 | 26.9 | 6 | 7.7 | |
Non-Injecting Illicit Drug Use Within Past Year | |||||||||||
Yes | 877 | 57.5 | 649 | 42.5 | 260 | 40.1 | 195 | 30.0 | 194 | 29.9 | |
No | 15,704 | 81.6 | 3,537 | 18.4 | 2,167 | 61.3 | 821 | 23.2 | 549 | 15.5 | |
Unknown or Missing | 189 | 72.1 | 73 | 27.9 | 46 | 63.0 | 20 | 27.4 | 7 | 9.6 | |
Resident of a Correction Facility at the Time of Diagnosis | |||||||||||
Yes | 463 | 70.2 | 197 | 29.8 | 94 | 47.7 | 50 | 25.4 | 53 | 26.9 | |
No | 16,192 | 80.1 | 4,018 | 19.9 | 2,353 | 58.6 | 970 | 24.1 | 695 | 17.3 | |
Unknown or Missing | 115 | 72.3 | 44 | 27.7 | 26 | 59.1 | 16 | 36.4 | 2 | 4.5 | |
HIV Status | |||||||||||
Positive | 809 | 76.0 | 255 | 24.0 | 135 | 52.9 | 56 | 22.0 | 64 | 25.1 | |
Negative | 14,089 | 79.4 | 3,660 | 20.6 | 2,110 | 57.7 | 908 | 24.8 | 642 | 17.5 | |
Refused | 397 | 86.3 | 63 | 13.7 | 46 | 73.0 | 12 | 19.0 | 5 | 7.9 | |
Not Offered | 991 | 82.2 | 215 | 17.8 | 136 | 63.3 | 46 | 21.4 | 33 | 15.3 | |
Unknown, Missing or Indeterminate | 484 | 88.0 | 66 | 12.0 | 46 | 69.7 | 14 | 21.2 | 6 | 9.1 | |
Multidrug-Resistant TB | |||||||||||
Yes | 245 | 81.1 | 57 | 18.9 | 36 | 63.2 | 7 | 12.3 | 14 | 24.6 | |
No | 15,893 | 79.8 | 4,027 | 20.2 | 2,337 | 58.0 | 982 | 24.4 | 708 | 17.6 | |
Unknown or Missing | 632 | 78.3 | 175 | 21.7 | 100 | 57.1 | 47 | 26.9 | 28 | 16.0 |
1 GENType clusters have two or more cases with matching spoligotype and 24-locus mycobacterial interspersed repetitive unit-variable number tandem repeat type (MIRU-VNTR) within a county during the specified 3-year time period.
2 Alert levels are based on a log-likelihood ratio (LLR), which calculates the geographical concentration of a genotype in a county compared to the rest of the country during a 3-year period.
3 There were 4,259 cases in 1,409 alerted clusters: 750 cases were in 76 (5.4%) high alert clusters; 1,036 cases were in 335 (23.8%) medium alert clusters, and 2,473 cases were in 998 (70.8%) non-alert clusters.
4 Cavitary disease only assessed for persons with pulmonary TB and an abnormal x-ray.
Note: Case counts for race categories (American Indian/Alaska Native, Asian, black/African American, Native Hawaiian/Other Pacific Islander, and white) are mutually exclusive and do not include persons of Hispanic ethnicity or multiple race. Multiple race does not include persons of Hispanic ethnicity.