Genomics Translation

Evaluation of Genomic Applications in Practice and Prevention (EGAPP)

In 2004, NOPHG launched the EGAPP initiative to establish and test a systematic, evidence-based process for evaluating genetic tests and other applications of genomic technology that are in transition from research to clinical and public health practice. 

A key EGAPP goal is to provide objective, timely, and credible information that is clearly linked to available scientific evidence. This information will allow health care providers and payers, consumers, policymakers, and others to distinguish genetic tests that are safe and useful.

Read more about the EGAPP initiative in the decade report (10 Years of Public Health Genomics at CDC 1997 - 2007)

How EGAPP Works

• EGAPP Steering Committee
  The EGAPP Steering Committee is a federal, interagency group that oversees the recruitment and selection of the independent EGAPP Working Group members.
• EGAPP Working Group
  The EGAPP Working Group is an independent group that develops recommendations and evidence-based reviews on genetic tests.
• EGAPP Stakeholders Group
  The EGAPP Stakeholders Group engages stakeholders in translating and disseminating EGAPP recommendations and reviews.

EGAPP Resources

• EGAPP References
• EGAPP Working Group Independent web site
• ACCE Model
• CDC-sponsored EGAPP evidence reports
• Recommendations by the EGAPP Working Group
• EGAPP initiative poster  (PDF 233KB)