“Population-based Prenatal Screening for Cystic Fibrosis via Carrier Testing” is a draft document produced by the Foundation for Blood Research (Scarborough, Maine) under a cooperative agreement (UR3/CCU319352) with the CDC, Office of Public Health Genomics. The ACCE project, named for the four components of evaluation—Analytic validity; Clinical validity; Clinical utility; and Ethical, legal, and social implications —is a model process for evaluating data on emerging genetic tests. The process consists of collecting, evaluating, and interpreting data about DNA-based tests and testing algorithms.

“Population-based Prenatal Screening for Cystic Fibrosis via Carrier Testing” is the first systematic review using the model process, with additional reviews under development.  The purpose of these reviews is to provide a comprehensive compilation of information and is intended for use by individuals and groups involved with shaping policy.  The document is not, in and of itself, intended to recommend policy.